Targeted Redox Regulation α-Ketoglutarate Dehydrogenase Complex for the Treatment of Human Diseases
α-ketoglutarate dehydrogenase complex (KGDHc) is a crucial enzyme in the tricarboxylic acid (TCA) cycle that intersects monosaccharides, amino acids, and fatty acid catabolism with oxidative phosphorylation (OxPhos). A key feature of KGDHc is its ability to sense changes in the redox environment thr...
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| Format: | Article |
| Language: | English |
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MDPI AG
2025-04-01
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| Series: | Cells |
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| Online Access: | https://www.mdpi.com/2073-4409/14/9/653 |
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