Controlled human malaria infection: overview and potential application in the evaluation of transmission-blocking interventions in malaria-endemic areas
Abstract Controlled human malaria infection (CHMI) involves the intentional infection of healthy individuals with malaria parasites, close observation of the volunteers, and clearance of the parasite at a predetermined endpoint. Depending on the need, CHMI can be initiated by either sporozoites or t...
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Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2025-02-01
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Series: | Malaria Journal |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12936-025-05277-x |
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