Imaging Assessment of Cardiovascular Disease in Systemic Lupus Erythematosus
Systemic lupus erythematosus is a multisystem, autoimmune disease known to be one of the strongest risk factors for atherosclerosis. Patients with SLE have an excess cardiovascular risk compared with the general population, leading to increased cardiovascular morbidity and mortality. Although the pr...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Clinical and Developmental Immunology |
| Online Access: | http://dx.doi.org/10.1155/2012/694143 |
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| author | Sara C. Croca Anisur Rahman |
| author_facet | Sara C. Croca Anisur Rahman |
| author_sort | Sara C. Croca |
| collection | DOAJ |
| description | Systemic lupus erythematosus is a multisystem, autoimmune disease known to be one of the strongest risk factors for atherosclerosis. Patients with SLE have an excess cardiovascular risk compared with the general population, leading to increased cardiovascular morbidity and mortality. Although the precise explanation for this is yet to be established, it seems to be associated with the presence of an accelerated atherosclerotic process, arising from the combination of traditional and lupus-specific risk factors. Moreover, cardiovascular-disease associated mortality in patients with SLE has not improved over time. One of the main reasons for this is the poor performance of standard risk stratification tools on assessing the cardiovascular risk of patients with SLE. Therefore, establishing alternative ways to identify patients at increased risk efficiently is essential. With recent developments in several imaging techniques, the ultimate goal of cardiovascular assessment will shift from assessing symptomatic patients to diagnosing early cardiovascular disease in asymptomatic patients which will hopefully help us to prevent its progression. This review will focus on the current status of the imaging tools available to assess cardiac and vascular function in patients with SLE. |
| format | Article |
| id | doaj-art-3a4cdc33d0774e128fb4e5dfeba59fb8 |
| institution | Kabale University |
| issn | 1740-2522 1740-2530 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical and Developmental Immunology |
| spelling | doaj-art-3a4cdc33d0774e128fb4e5dfeba59fb82025-02-03T01:04:45ZengWileyClinical and Developmental Immunology1740-25221740-25302012-01-01201210.1155/2012/694143694143Imaging Assessment of Cardiovascular Disease in Systemic Lupus ErythematosusSara C. Croca0Anisur Rahman1Centre for Rheumatology, Division of Medicine, University College London, London WC1E 6JF, UKCentre for Rheumatology, Division of Medicine, University College London, London WC1E 6JF, UKSystemic lupus erythematosus is a multisystem, autoimmune disease known to be one of the strongest risk factors for atherosclerosis. Patients with SLE have an excess cardiovascular risk compared with the general population, leading to increased cardiovascular morbidity and mortality. Although the precise explanation for this is yet to be established, it seems to be associated with the presence of an accelerated atherosclerotic process, arising from the combination of traditional and lupus-specific risk factors. Moreover, cardiovascular-disease associated mortality in patients with SLE has not improved over time. One of the main reasons for this is the poor performance of standard risk stratification tools on assessing the cardiovascular risk of patients with SLE. Therefore, establishing alternative ways to identify patients at increased risk efficiently is essential. With recent developments in several imaging techniques, the ultimate goal of cardiovascular assessment will shift from assessing symptomatic patients to diagnosing early cardiovascular disease in asymptomatic patients which will hopefully help us to prevent its progression. This review will focus on the current status of the imaging tools available to assess cardiac and vascular function in patients with SLE.http://dx.doi.org/10.1155/2012/694143 |
| spellingShingle | Sara C. Croca Anisur Rahman Imaging Assessment of Cardiovascular Disease in Systemic Lupus Erythematosus Clinical and Developmental Immunology |
| title | Imaging Assessment of Cardiovascular Disease in Systemic Lupus Erythematosus |
| title_full | Imaging Assessment of Cardiovascular Disease in Systemic Lupus Erythematosus |
| title_fullStr | Imaging Assessment of Cardiovascular Disease in Systemic Lupus Erythematosus |
| title_full_unstemmed | Imaging Assessment of Cardiovascular Disease in Systemic Lupus Erythematosus |
| title_short | Imaging Assessment of Cardiovascular Disease in Systemic Lupus Erythematosus |
| title_sort | imaging assessment of cardiovascular disease in systemic lupus erythematosus |
| url | http://dx.doi.org/10.1155/2012/694143 |
| work_keys_str_mv | AT saraccroca imagingassessmentofcardiovasculardiseaseinsystemiclupuserythematosus AT anisurrahman imagingassessmentofcardiovasculardiseaseinsystemiclupuserythematosus |