Prolonged release pirfenidone restores miRNA expression and CpG island methylation in patients with HCV sustained virological response and residual liver fibrosis

Prolonged release pirfenidone restores miRNA expression and CpG island methylation in patients with HCV sustained virological response and residual liver fibrosis

Introduction and Objectives: Patients with residual liver fibrosis after hepatitis C virus-infection clearance represent an important challenge due to the risk of progression and hepatocarcinoma development. The primary end of this study was to evaluate epigenetic marks in DAA-responders HCV non-Eur...

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Main Authors: Eira Cerda-Reyes, Ricardo de la Rosa-Bibiano, Ana Sandoval-Rodriguez, Rebeca Rosas-Campos, Rebeca Escutia-Gutiérrez, Ángel Vázquez-Esqueda, Stefanny Cornejo-Hernández, Alejandro Gutiérrez-Átemis, Salvador Amezquita-Pérez, Jorge Luis Poo, Gildardo Agustin Garrido-Sanchez, Juan Ramón-Aguilar, Juan Armendáriz-Borunda
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Annals of Hepatology
Online Access:http://www.sciencedirect.com/science/article/pii/S1665268125001139
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