Network dynamics-based subtyping of Alzheimer’s disease with microglial genetic risk factors

Network dynamics-based subtyping of Alzheimer’s disease with microglial genetic risk factors

Abstract Background The potential of microglia as a target for Alzheimer’s disease (AD) treatment is promising, yet the clinical and pathological diversity within microglia, driven by genetic factors, poses a significant challenge. Subtyping AD is imperative to enable precise and effective treatment...

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Bibliographic Details
Main Authors: Jae Hyuk Choi, Jonghoon Lee, Uiryong Kang, Hongjun Chang, Kwang-Hyun Cho
Format: Article
Language:English
Published: BMC 2024-10-01
Series:Alzheimer’s Research & Therapy
Subjects:
Alzheimer’s disease
Microglia
Network dynamics
Genetic risk factors
Patient subtyping
Systems biology
Online Access:https://doi.org/10.1186/s13195-024-01583-9
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https://doi.org/10.1186/s13195-024-01583-9

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