Asprosin‐FABP5 Interaction Modulates Mitochondrial Fatty Acid Oxidation through PPARα Contributing to MASLD Development

Asprosin‐FABP5 Interaction Modulates Mitochondrial Fatty Acid Oxidation through PPARα Contributing to MASLD Development

Abstract Alterations in liver metabolism play a pivotal role in the development and progression of metabolic dysfunction‐associated steatotic liver disease (MASLD). Asprosin is reported to be released from white adipose tissue during fasting and targets the liver. However, the role of asprosin, espe...

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Main Authors: Yuan‐Yuan Yu, Min Feng, Yi Chen, Hong‐Lin Jia, Qi Zhang, Ming Tong, Yan‐Xi Li, Yu Zhao, Xin‐Xin Liu, Shi‐Feng Cao, Zheng‐kai Wang, Hou‐wei Li, Xue Liu, Yan Zhang
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:Advanced Science
Subjects:
asprosin
FABP5
fenofibrate
hepatic steatosis
insulin resistance
mitochondrial fatty acid β‐oxidation
Online Access:https://doi.org/10.1002/advs.202415846
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https://doi.org/10.1002/advs.202415846

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