Synthesis and Antimicrobial Screening of Quinazolone Containing Novel Heterocyclic Schiff Base and Azetidinone by Niementowski Reaction

Several 2-[2-{(4-substitutedbenzylidene)-phenyl}vinyl]-4-oxo-3,4-dihydroquinazolone-6-sulfonicacid 4(a-l) and 2-[2-{4-(3-chloro-4-substituedphenyl-azetidin-2-one)-phenyl}vinyl]-4-oxo-3,4-dihydroqui-nazolone-6-sulfonic acid 5(a-l) were synthesized by using conventional techniques and were screened fo...

Full description

Saved in:
Bibliographic Details
Main Authors: A. R. Desai, R. U. Roy, K. R. Desai
Format: Article
Language:English
Published: Wiley 2005-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2005/796474
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832561827968450560
author A. R. Desai
R. U. Roy
K. R. Desai
author_facet A. R. Desai
R. U. Roy
K. R. Desai
author_sort A. R. Desai
collection DOAJ
description Several 2-[2-{(4-substitutedbenzylidene)-phenyl}vinyl]-4-oxo-3,4-dihydroquinazolone-6-sulfonicacid 4(a-l) and 2-[2-{4-(3-chloro-4-substituedphenyl-azetidin-2-one)-phenyl}vinyl]-4-oxo-3,4-dihydroqui-nazolone-6-sulfonic acid 5(a-l) were synthesized by using conventional techniques and were screened for antibacterial and antifungal activity. The compounds showed good to moderate antimicrobial activity and were characterized on the basis of spectral analysis.
format Article
id doaj-art-39f623a36e30455c964a5dc9e515ebb0
institution Kabale University
issn 0973-4945
2090-9810
language English
publishDate 2005-01-01
publisher Wiley
record_format Article
series E-Journal of Chemistry
spelling doaj-art-39f623a36e30455c964a5dc9e515ebb02025-02-03T01:24:01ZengWileyE-Journal of Chemistry0973-49452090-98102005-01-012210110810.1155/2005/796474Synthesis and Antimicrobial Screening of Quinazolone Containing Novel Heterocyclic Schiff Base and Azetidinone by Niementowski ReactionA. R. Desai0R. U. Roy1K. R. Desai2Department of chemistry, Veer Narmad South Gujarat University, Surat-395007, IndiaDepartment of chemistry, Veer Narmad South Gujarat University, Surat-395007, IndiaDepartment of chemistry, Veer Narmad South Gujarat University, Surat-395007, IndiaSeveral 2-[2-{(4-substitutedbenzylidene)-phenyl}vinyl]-4-oxo-3,4-dihydroquinazolone-6-sulfonicacid 4(a-l) and 2-[2-{4-(3-chloro-4-substituedphenyl-azetidin-2-one)-phenyl}vinyl]-4-oxo-3,4-dihydroqui-nazolone-6-sulfonic acid 5(a-l) were synthesized by using conventional techniques and were screened for antibacterial and antifungal activity. The compounds showed good to moderate antimicrobial activity and were characterized on the basis of spectral analysis.http://dx.doi.org/10.1155/2005/796474
spellingShingle A. R. Desai
R. U. Roy
K. R. Desai
Synthesis and Antimicrobial Screening of Quinazolone Containing Novel Heterocyclic Schiff Base and Azetidinone by Niementowski Reaction
E-Journal of Chemistry
title Synthesis and Antimicrobial Screening of Quinazolone Containing Novel Heterocyclic Schiff Base and Azetidinone by Niementowski Reaction
title_full Synthesis and Antimicrobial Screening of Quinazolone Containing Novel Heterocyclic Schiff Base and Azetidinone by Niementowski Reaction
title_fullStr Synthesis and Antimicrobial Screening of Quinazolone Containing Novel Heterocyclic Schiff Base and Azetidinone by Niementowski Reaction
title_full_unstemmed Synthesis and Antimicrobial Screening of Quinazolone Containing Novel Heterocyclic Schiff Base and Azetidinone by Niementowski Reaction
title_short Synthesis and Antimicrobial Screening of Quinazolone Containing Novel Heterocyclic Schiff Base and Azetidinone by Niementowski Reaction
title_sort synthesis and antimicrobial screening of quinazolone containing novel heterocyclic schiff base and azetidinone by niementowski reaction
url http://dx.doi.org/10.1155/2005/796474
work_keys_str_mv AT ardesai synthesisandantimicrobialscreeningofquinazolonecontainingnovelheterocyclicschiffbaseandazetidinonebyniementowskireaction
AT ruroy synthesisandantimicrobialscreeningofquinazolonecontainingnovelheterocyclicschiffbaseandazetidinonebyniementowskireaction
AT krdesai synthesisandantimicrobialscreeningofquinazolonecontainingnovelheterocyclicschiffbaseandazetidinonebyniementowskireaction