Synthesis and Antimicrobial Screening of Quinazolone Containing Novel Heterocyclic Schiff Base and Azetidinone by Niementowski Reaction

Several 2-[2-{(4-substitutedbenzylidene)-phenyl}vinyl]-4-oxo-3,4-dihydroquinazolone-6-sulfonicacid 4(a-l) and 2-[2-{4-(3-chloro-4-substituedphenyl-azetidin-2-one)-phenyl}vinyl]-4-oxo-3,4-dihydroqui-nazolone-6-sulfonic acid 5(a-l) were synthesized by using conventional techniques and were screened fo...

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Bibliographic Details
Main Authors: A. R. Desai, R. U. Roy, K. R. Desai
Format: Article
Language:English
Published: Wiley 2005-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2005/796474
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Summary:Several 2-[2-{(4-substitutedbenzylidene)-phenyl}vinyl]-4-oxo-3,4-dihydroquinazolone-6-sulfonicacid 4(a-l) and 2-[2-{4-(3-chloro-4-substituedphenyl-azetidin-2-one)-phenyl}vinyl]-4-oxo-3,4-dihydroqui-nazolone-6-sulfonic acid 5(a-l) were synthesized by using conventional techniques and were screened for antibacterial and antifungal activity. The compounds showed good to moderate antimicrobial activity and were characterized on the basis of spectral analysis.
ISSN:0973-4945
2090-9810