The microbiota-derived bile acid taurodeoxycholic acid improves hepatic cholesterol levels in mice with cancer cachexia

The microbiota-derived bile acid taurodeoxycholic acid improves hepatic cholesterol levels in mice with cancer cachexia

Alterations in bile acid profile and pathways contribute to hepatic inflammation in cancer cachexia, a syndrome worsening the prognosis of cancer patients. As the gut microbiota impinges on host metabolism through bile acids, the current study aimed to explore the functional contribution of gut micr...

Full description

Saved in:
Bibliographic Details
Main Authors: Morgane M. Thibaut, Martin Roumain, Edwige Piron, Justine Gillard, Axelle Loriot, Audrey M. Neyrinck, Julie Rodriguez, Isabelle Massart, Jean-Paul Thissen, Joshua R. Huot, Fabrizio Pin, Andrea Bonetto, Nathalie M. Delzenne, Giulio G. Muccioli, Laure B. Bindels
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Gut Microbes
Subjects:
Cancer cachexia
bile acids
gut microbiota
muscle atrophy
liver
Xylanibacter
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2025.2449586
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.tandfonline.com/doi/10.1080/19490976.2025.2449586

Similar Items