Evaluation of three novel antigens and costimulatory agents for improvement of M. Tuberculosis specific interferon gamma release assays

Evaluation of three novel antigens and costimulatory agents for improvement of M. Tuberculosis specific interferon gamma release assays

Abstract Background Mycobacterium tuberculosis (MT) infections represent a global health problem and latent tuberculosis infection (LTBI) affects an estimated 25% of the world population. 10.6 million people fell ill with tuberculosis (TB) worldwide in 2021 and a total of 1.6 million TB-associated d...

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Bibliographic Details
Main Authors: Sandra Schwarzlose-Schwarck, Mark Reinwald, Torsten Bauer, Florian Hentschel, Til Kiderlen, Dorinja Zapf, Victor Herbst, Stefan Lüth, David Krieger, Werner Dammermann
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Infectious Diseases
Subjects:
Tuberculosis
IGRA
Complement factors
TLR agonists
Interferon gamma release assay
Online Access:https://doi.org/10.1186/s12879-025-10577-3
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