Resolution of Refractory Status Epilepticus With Ketamine Without Intubation in a Patient With Stroke-Like Migraine Attacks After Radiation Therapy (SMART) Syndrome
Stroke-like migraine attacks after radiation therapy (SMART) syndrome is an infrequently reported complication arising years after radiation therapy that manifests as a reversible syndrome marked by migraine-like headaches, focal neurologic signs, and/or seizures. Refractory status epilepticus (RSE)...
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Language: | English |
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Wiley
2025-01-01
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Series: | Case Reports in Neurological Medicine |
Online Access: | http://dx.doi.org/10.1155/crnm/3203322 |
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author | Kyle N. Kaneko Pablo Read John M. Eaton Yoshie Umemura Justin L. Hoskin |
author_facet | Kyle N. Kaneko Pablo Read John M. Eaton Yoshie Umemura Justin L. Hoskin |
author_sort | Kyle N. Kaneko |
collection | DOAJ |
description | Stroke-like migraine attacks after radiation therapy (SMART) syndrome is an infrequently reported complication arising years after radiation therapy that manifests as a reversible syndrome marked by migraine-like headaches, focal neurologic signs, and/or seizures. Refractory status epilepticus (RSE) associated with SMART syndrome is rare and can be challenging to treat. Valproic acid has been reported to improve seizures in RSE in SMART syndrome in a few case reports and may be ideal for SMART syndrome, given its use in the treatment of migraines and seizures. Ketamine has been used in RSE and a few instances in SMART syndrome. Here, we present a case of refractory focal status epilepticus in a patient with SMART syndrome who was treated with ketamine, which resolved seizures without the need for intubation. |
format | Article |
id | doaj-art-395799d01cac44c6b2238a1c5d13dacb |
institution | Kabale University |
issn | 2090-6676 |
language | English |
publishDate | 2025-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Neurological Medicine |
spelling | doaj-art-395799d01cac44c6b2238a1c5d13dacb2025-02-12T05:00:04ZengWileyCase Reports in Neurological Medicine2090-66762025-01-01202510.1155/crnm/3203322Resolution of Refractory Status Epilepticus With Ketamine Without Intubation in a Patient With Stroke-Like Migraine Attacks After Radiation Therapy (SMART) SyndromeKyle N. Kaneko0Pablo Read1John M. Eaton2Yoshie Umemura3Justin L. Hoskin4Department of NeurologyDepartment of NeurologyDepartment of NeurologyDepartment of NeurologyDepartment of NeurologyStroke-like migraine attacks after radiation therapy (SMART) syndrome is an infrequently reported complication arising years after radiation therapy that manifests as a reversible syndrome marked by migraine-like headaches, focal neurologic signs, and/or seizures. Refractory status epilepticus (RSE) associated with SMART syndrome is rare and can be challenging to treat. Valproic acid has been reported to improve seizures in RSE in SMART syndrome in a few case reports and may be ideal for SMART syndrome, given its use in the treatment of migraines and seizures. Ketamine has been used in RSE and a few instances in SMART syndrome. Here, we present a case of refractory focal status epilepticus in a patient with SMART syndrome who was treated with ketamine, which resolved seizures without the need for intubation.http://dx.doi.org/10.1155/crnm/3203322 |
spellingShingle | Kyle N. Kaneko Pablo Read John M. Eaton Yoshie Umemura Justin L. Hoskin Resolution of Refractory Status Epilepticus With Ketamine Without Intubation in a Patient With Stroke-Like Migraine Attacks After Radiation Therapy (SMART) Syndrome Case Reports in Neurological Medicine |
title | Resolution of Refractory Status Epilepticus With Ketamine Without Intubation in a Patient With Stroke-Like Migraine Attacks After Radiation Therapy (SMART) Syndrome |
title_full | Resolution of Refractory Status Epilepticus With Ketamine Without Intubation in a Patient With Stroke-Like Migraine Attacks After Radiation Therapy (SMART) Syndrome |
title_fullStr | Resolution of Refractory Status Epilepticus With Ketamine Without Intubation in a Patient With Stroke-Like Migraine Attacks After Radiation Therapy (SMART) Syndrome |
title_full_unstemmed | Resolution of Refractory Status Epilepticus With Ketamine Without Intubation in a Patient With Stroke-Like Migraine Attacks After Radiation Therapy (SMART) Syndrome |
title_short | Resolution of Refractory Status Epilepticus With Ketamine Without Intubation in a Patient With Stroke-Like Migraine Attacks After Radiation Therapy (SMART) Syndrome |
title_sort | resolution of refractory status epilepticus with ketamine without intubation in a patient with stroke like migraine attacks after radiation therapy smart syndrome |
url | http://dx.doi.org/10.1155/crnm/3203322 |
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