Degradation of amyloid β-peptides catalyzed by nattokinase in vivo and in vitro

Amyloid-β 1-42 (Aβ42) plays a pivotal role in Alzheimer disease (AD) pathogenesis. Peripheral clearance of Aβ42 largely affects its level in the brain and affects AD progression. Although nattokinase (NK) degrades Aβ40, the details of NK’s capture of various Aβ species and reduction of plasma Aβ42/A...

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Bibliographic Details
Main Authors: Aixin Ni, He Li, Ruya Wang, Rentong Sun, Yingjiu Zhang
Format: Article
Language:English
Published: Tsinghua University Press 2023-09-01
Series:Food Science and Human Wellness
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Online Access:http://www.sciencedirect.com/science/article/pii/S2213453023000423
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