Intraperitoneal infection of A/J and CD1 mice with coxsackievirus B2 and its mutants

Intraperitoneal infection of A/J and CD1 mice with coxsackievirus B2 and its mutants

Coxsackieviruses (CVs) belong to the genus Enterovirus and family Picornaviridae. Mutants can arise within the replication cycle of RNA viruses. The prototype CVB2 Ohio-1 (CVB2/O) strain adapted to rhabdomyosarcoma (RD) cells induced cytolytic infection and showed three-point mutations in the genome...

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Bibliographic Details
Main Authors: Maria Borsanyiova, Katarina Berakova, Brigita Benkoova, Michaela Pellerova, A. Michael Lindberg, Shubhada Bopegamage
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Acta Virologica
Subjects:
coxsackievirus B2
mouse model
intraperitoneal infection
pathogenesis
mutant
Online Access:https://www.frontierspartnerships.org/articles/10.3389/av.2025.12740/full
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