Induction of Immune Responses in Mice and Newborn Piglets by Oral Immunization with Recombinant <i>Lactococcus lactis</i> Expressing S1 and M Proteins of Porcine Epidemic Diarrhea Virus

Induction of Immune Responses in Mice and Newborn Piglets by Oral Immunization with Recombinant <i>Lactococcus lactis</i> Expressing S1 and M Proteins of Porcine Epidemic Diarrhea Virus

Porcine epidemic diarrhea (PED) is a severe gastrointestinal disease caused by the porcine epidemic diarrhea virus (PEDV), a virus that spreads through the intestinal tract, leading to significant economic losses in the global swine industry. Therefore, compared to traditional injection method, deve...

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Bibliographic Details
Main Authors: Xiulei Cai, Zhikui Wang, Xinping Yan, Xu Wang, Xiaoxue Yue, Hongliang Zhang
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Microorganisms
Subjects:
porcine epidemic diarrhea virus
<i>Lactococcus lactis</i>
oral immunization
immunogenicity evaluation
mice and piglets
Online Access:https://www.mdpi.com/2076-2607/13/4/714
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