Identification of new process-related impurity in the key intermediate in the synthesis of TCV-116

Development of safe and effective drugs requires complete impurity evaluation and, therefore, knowledge about the formation and elimination of impurities is necessary. During impurity profiling of a key intermediate during synthesis of candesartan cilexetil (1-(((cyclohexyloxy)carbonyl) oxy)ethyl 1-...

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Bibliographic Details
Main Authors: Testen Ana, Plevnik Miha, Štefane Bogdan, Cigić Irena Kralj
Format: Article
Language:English
Published: Sciendo 2019-03-01
Series:Acta Pharmaceutica
Subjects:
Online Access:https://doi.org/10.2478/acph-2019-0006
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