Tumor mutation burden for predicting immune checkpoint blockade response: the more, the better
Background Recently, the US Food and Drug Administration (FDA) has approved immune checkpoint blockade (ICB) for treating cancer patients with tumor mutation burden (TMB) >10 mutations/megabase (mut/Mb). However, high TMB (TMB-H) defined by >10 mut/Mb fails to predict ICB response acro...
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Main Author: | |
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Format: | Article |
Language: | English |
Published: |
BMJ Publishing Group
2022-01-01
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Series: | Journal for ImmunoTherapy of Cancer |
Online Access: | https://jitc.bmj.com/content/10/1/e003087.full |
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