Incidence Of Helicobacter Pylori Infection in Association With ABO Blood Groups
Objective: The study aimed to investigate the association between ABO blood groups and helicobacter infection. Method: 150 participants, including 93 females and 57 males between the age group of 18-60 years, were involved in the study. A sample of 3 ml blood was collected and screened against H....
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Rawalpindi Medical University
2024-03-01
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| Series: | Journal of Rawalpindi Medical College |
| Subjects: | |
| Online Access: | https://www.journalrmc.com/index.php/JRMC/article/view/2423 |
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| Summary: | Objective: The study aimed to investigate the association between ABO blood groups and helicobacter infection.
Method: 150 participants, including 93 females and 57 males between the age group of 18-60 years, were involved in the study. A sample of 3 ml blood was collected and screened against H. pylori antibodies (IgG) by H. pylori rapid diagnostic kit. ABO and Lewis antigen phenotypes were determined with a macroscopic agglutination technique.
Results: According to the study's findings, there were 55.42% women (46/83) and 44.5% men (37/83) among the 83 seropositive patients, while 70.14% women (47/67) and 29.85% men (20/67) were found among the 67 seronegative patients. The findings of this study reveal that those with the blood groups O+ and B+ have an estimated 25.3% (21/83) higher risk of H. pylori infection, whereas when seronegative individuals were investigated, it was discovered that blood groups 0+ were also leading, 28.4% (19/67), indicating that there was no significant difference between H. pylori seropositive and seronegative patients (p-value = 0.5146). Other factors, such as gender and family history, did not significantly affect the incidence of H. pylori.
Conclusion: It was concluded from the study that no significant difference was observed between trends of H. pylori seropositive patients and seronegative individuals having different blood groups.
Keywords: ABO Blood Group, Peptic Ulcer, Seronegative Pyloric patients, Seropositive Pyloric patients.
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| ISSN: | 1683-3562 1683-3570 |