Vaccines and Immunotherapeutics for the Treatment of Malignant Disease
The employment of the immune system to treat malignant disease represents an active area of biomedical research. The specificity of the immune response and potential for establishing long-term tumor immunity compels researchers to continue investigations into immunotherapeutic approaches for cancer....
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2010-01-01
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| Series: | Clinical and Developmental Immunology |
| Online Access: | http://dx.doi.org/10.1155/2010/697158 |
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| _version_ | 1832558712987844608 |
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| author | Joel F. Aldrich Devin B. Lowe Michael H. Shearer Richard E. Winn Cynthia A. Jumper Ronald C. Kennedy |
| author_facet | Joel F. Aldrich Devin B. Lowe Michael H. Shearer Richard E. Winn Cynthia A. Jumper Ronald C. Kennedy |
| author_sort | Joel F. Aldrich |
| collection | DOAJ |
| description | The employment of the immune system to treat malignant disease represents an active area of biomedical research. The specificity of the immune response and potential for establishing long-term tumor immunity compels researchers to continue investigations into immunotherapeutic approaches for cancer. A number of immunotherapeutic strategies have arisen for the treatment of malignant disease, including various vaccination schemes, cytokine therapy, adoptive cellular therapy, and monoclonal antibody therapy. This paper describes each of these strategies and discusses some of the associated successes and limitations. Emphasis is placed on the integration of techniques to promote optimal scenarios for eliminating cancer. |
| format | Article |
| id | doaj-art-381b7793dd1d43f1949ef8b032c45402 |
| institution | Kabale University |
| issn | 1740-2522 1740-2530 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical and Developmental Immunology |
| spelling | doaj-art-381b7793dd1d43f1949ef8b032c454022025-02-03T01:31:40ZengWileyClinical and Developmental Immunology1740-25221740-25302010-01-01201010.1155/2010/697158697158Vaccines and Immunotherapeutics for the Treatment of Malignant DiseaseJoel F. Aldrich0Devin B. Lowe1Michael H. Shearer2Richard E. Winn3Cynthia A. Jumper4Ronald C. Kennedy5Department of Microbiology and Immunology, Texas Tech University Health Sciences Center, 3601 4th Street, MS 6591, Lubbock, TX 79430, USADepartment of Microbiology and Immunology, Texas Tech University Health Sciences Center, 3601 4th Street, MS 6591, Lubbock, TX 79430, USADepartment of Microbiology and Immunology, Texas Tech University Health Sciences Center, 3601 4th Street, MS 6591, Lubbock, TX 79430, USADepartment of Microbiology and Immunology, Texas Tech University Health Sciences Center, 3601 4th Street, MS 6591, Lubbock, TX 79430, USADepartment of Microbiology and Immunology, Texas Tech University Health Sciences Center, 3601 4th Street, MS 6591, Lubbock, TX 79430, USADepartment of Microbiology and Immunology, Texas Tech University Health Sciences Center, 3601 4th Street, MS 6591, Lubbock, TX 79430, USAThe employment of the immune system to treat malignant disease represents an active area of biomedical research. The specificity of the immune response and potential for establishing long-term tumor immunity compels researchers to continue investigations into immunotherapeutic approaches for cancer. A number of immunotherapeutic strategies have arisen for the treatment of malignant disease, including various vaccination schemes, cytokine therapy, adoptive cellular therapy, and monoclonal antibody therapy. This paper describes each of these strategies and discusses some of the associated successes and limitations. Emphasis is placed on the integration of techniques to promote optimal scenarios for eliminating cancer.http://dx.doi.org/10.1155/2010/697158 |
| spellingShingle | Joel F. Aldrich Devin B. Lowe Michael H. Shearer Richard E. Winn Cynthia A. Jumper Ronald C. Kennedy Vaccines and Immunotherapeutics for the Treatment of Malignant Disease Clinical and Developmental Immunology |
| title | Vaccines and Immunotherapeutics for the Treatment of Malignant Disease |
| title_full | Vaccines and Immunotherapeutics for the Treatment of Malignant Disease |
| title_fullStr | Vaccines and Immunotherapeutics for the Treatment of Malignant Disease |
| title_full_unstemmed | Vaccines and Immunotherapeutics for the Treatment of Malignant Disease |
| title_short | Vaccines and Immunotherapeutics for the Treatment of Malignant Disease |
| title_sort | vaccines and immunotherapeutics for the treatment of malignant disease |
| url | http://dx.doi.org/10.1155/2010/697158 |
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