Key Role of Human ABC Transporter ABCG2 in Photodynamic Therapy and Photodynamic Diagnosis
Accumulating evidence indicates that ATP-binding cassette (ABC) transporter ABCG2 plays a key role in regulating the cellular accumulation of porphyrin derivatives in cancer cells and thereby affects the efficacy of photodynamic therapy and photodynamic diagnosis. The activity of porphyrin efflux ca...
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Main Authors: | Toshihisa Ishikawa, Hiroshi Nakagawa, Yuichiro Hagiya, Naosuke Nonoguchi, Shin-ichi Miyatake, Toshihiko Kuroiwa |
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Format: | Article |
Language: | English |
Published: |
Wiley
2010-01-01
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Series: | Advances in Pharmacological Sciences |
Online Access: | http://dx.doi.org/10.1155/2010/587306 |
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