Key Role of Human ABC Transporter ABCG2 in Photodynamic Therapy and Photodynamic Diagnosis

Accumulating evidence indicates that ATP-binding cassette (ABC) transporter ABCG2 plays a key role in regulating the cellular accumulation of porphyrin derivatives in cancer cells and thereby affects the efficacy of photodynamic therapy and photodynamic diagnosis. The activity of porphyrin efflux ca...

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Bibliographic Details
Main Authors: Toshihisa Ishikawa, Hiroshi Nakagawa, Yuichiro Hagiya, Naosuke Nonoguchi, Shin-ichi Miyatake, Toshihiko Kuroiwa
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Advances in Pharmacological Sciences
Online Access:http://dx.doi.org/10.1155/2010/587306
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