Vγ9Vδ2 T cells expanded with vitamin C combined with HMBPP in vitro inhibit intracellular Mycobacterium tuberculosis growth

Vγ9Vδ2 T cells expanded with vitamin C combined with HMBPP in vitro inhibit intracellular Mycobacterium tuberculosis growth

BackgroundMycobacterium tuberculosis (Mtb) presents a significant global health threat, and the existing treatments have notable limitations. Vγ9Vδ2 T cells activated by HMBPP can inhibit the growth of intracellular Mtb. Additionally, vitamin C (VC) promotes the differentiation and proliferation of...

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Bibliographic Details
Main Authors: Shuyan Liu, Guohui Xiao, Wanxin Liang, Su Zhang, Juan Liang, Teng Pan, Shaoxiang Lin, Xiuju Liu, Zhenwen Zhou, Guoliang Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Mycobacterium tuberculosis
Vγ9Vδ2 T cells
HMBPP
vitamin C
induction rate
effector function
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1533277/full
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https://www.frontiersin.org/articles/10.3389/fcimb.2025.1533277/full

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