Neurotrophic factor Neuritin modulates T cell electrical and metabolic state for the balance of tolerance and immunity

Neurotrophic factor Neuritin modulates T cell electrical and metabolic state for the balance of tolerance and immunity

The adaptive T cell response is accompanied by continuous rewiring of the T cell’s electric and metabolic state. Ion channels and nutrient transporters integrate bioelectric and biochemical signals from the environment, setting cellular electric and metabolic states. Divergent electric and metabolic...

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Bibliographic Details
Main Authors: Hong Yu, Hiroshi Nishio, Joseph Barbi, Marisa Mitchell-Flack, Paolo DA Vignali, Ying Zheng, Andriana Lebid, Kwang-Yu Chang, Juan Fu, Makenzie Higgins, Ching-Tai Huang, Xuehong Zhang, Zhiguang Li, Lee Blosser, Ada Tam, Charles Drake, Drew Pardoll
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-11-01
Series:eLife
Subjects:
electric state
metabolism
Treg
effector T cell
autoimmunity
cell fate
Online Access:https://elifesciences.org/articles/96812
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https://elifesciences.org/articles/96812

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