TGF-β1/Smads and miR-21 in Renal Fibrosis and Inflammation

Renal fibrosis, irrespective of its etiology, is a final common stage of almost all chronic kidney diseases. Increased apoptosis, epithelial-to-mesenchymal transition, and inflammatory cell infiltration characterize the injured kidney. On the molecular level, transforming growth factor-β1 (TGF-β1)-S...

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Bibliographic Details
Main Authors: Agnieszka Loboda, Mateusz Sobczak, Alicja Jozkowicz, Jozef Dulak
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2016/8319283
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