Heptamethine cyanine-based polymeric nanoparticles for photothermal therapy in HCT116 human colon cancer model

Heptamethine cyanine-based polymeric nanoparticles for photothermal therapy in HCT116 human colon cancer model

Abstract In this work, we synthesize a quinoline-based heptamethine cyanine, QuCy7, with sulfonate groups to enhance water solubility. This dye demonstrates exceptional near-infrared absorption beyond 750 nm, accompanied by photothermal properties but low photostability. Encapsulating QyCy7 with pol...

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Main Authors: Sastiya Kampaengsri, Gong Yi Yong, Sirimongkon Aryamueang, Bongkot Ouengwanarat, Thitima Pewklang, Kantapat Chansaenpak, Sarawut Jitrapakdee, Chin-Siang Kue, Anyanee Kamkaew
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
NIR photosensitizer
PTT
cancer therapy
nanomedicine
heptamethine cyanine
chick embryo
Online Access:https://doi.org/10.1038/s41598-024-83249-y
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https://doi.org/10.1038/s41598-024-83249-y

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