Licochalcone D inhibits osteoclast differentiation and postmenopausal osteoporosis by inactivating the NF-κB signaling pathway

Abstract Background Osteoporosis is prevalent among postmenopausal women and is characterized by excessive bone resorption primarily mediated by osteoclasts. This study aimed to investigate the effects of the natural compound Licochalcone D (Lico D) on osteoclast differentiation and its therapeutic...

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Bibliographic Details
Main Authors: Xiaoyi Shen, Qian Zhang, Jingjing Ding, Jun Zhou, Sasa Tan, Xianzhen Feng, Zhongqing Xu, Fei Hua
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Online Access:https://doi.org/10.1186/s13018-025-06132-0
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