Discovery and in vitro characterization of a human anti-CD36 scFv

Discovery and in vitro characterization of a human anti-CD36 scFv

IntroductionCD36 is a membrane receptor that participates in the cellular uptake of fatty acids and lipid metabolism. CD36 overexpression favors progression of different pathologies, such as atherosclerosis and cancer. Thus, CD36 targeting has medicinal relevance. Herein, we aimed to identify human...

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Main Authors: Cecilia Mata-Cruz, Sandra L. Guerrero-Rodríguez, Keyla Gómez-Castellano, Gregorio Carballo-Uicab, Juan Carlos Almagro, S. Mayra Pérez-Tapia, Marco A. Velasco-Velázquez
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Immunology
Subjects:
CD36
scFv antibodies
cancer
atherosclerotic cardiovascular disease
phage display
human antibodies
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1531171/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1531171/full

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