Insufficient Humidification of Respiratory Gases in Patients Who Are Undergoing Therapeutic Hypothermia at a Paediatric and Adult Intensive Care Unit

For cooled newborn infants, humidifier settings for normothermic condition provide excessive gas humidity because absolute humidity at saturation is temperature-dependent. To assess humidification of respiratory gases in patients who underwent moderate therapeutic hypothermia at a paediatric/adult i...

Full description

Saved in:
Bibliographic Details
Main Authors: Yukari Tanaka, Sachiko Iwata, Masahiro Kinoshita, Kennosuke Tsuda, Shoichiro Tanaka, Naoko Hara, Ryota Shindou, Eimei Harada, Ryouji Kijima, Osamu Yamaga, Hitoe Ohkuma, Kazuo Ushijima, Teruo Sakamoto, Yushiro Yamashita, Osuke Iwata
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Canadian Respiratory Journal
Online Access:http://dx.doi.org/10.1155/2017/8349874
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832565914977959936
author Yukari Tanaka
Sachiko Iwata
Masahiro Kinoshita
Kennosuke Tsuda
Shoichiro Tanaka
Naoko Hara
Ryota Shindou
Eimei Harada
Ryouji Kijima
Osamu Yamaga
Hitoe Ohkuma
Kazuo Ushijima
Teruo Sakamoto
Yushiro Yamashita
Osuke Iwata
author_facet Yukari Tanaka
Sachiko Iwata
Masahiro Kinoshita
Kennosuke Tsuda
Shoichiro Tanaka
Naoko Hara
Ryota Shindou
Eimei Harada
Ryouji Kijima
Osamu Yamaga
Hitoe Ohkuma
Kazuo Ushijima
Teruo Sakamoto
Yushiro Yamashita
Osuke Iwata
author_sort Yukari Tanaka
collection DOAJ
description For cooled newborn infants, humidifier settings for normothermic condition provide excessive gas humidity because absolute humidity at saturation is temperature-dependent. To assess humidification of respiratory gases in patients who underwent moderate therapeutic hypothermia at a paediatric/adult intensive care unit, 6 patients were studied over 9 times. Three humidifier settings, 37-default (chamber-outlet, 37°C; Y-piece, 40°C), 33.5-theoretical (chamber-outlet, 33.5°C; Y-piece, 36.5°C), and 33.5-adjusted (optimised setting to achieve saturated vapour at 33.5°C using feedback from a thermohygrometer), were tested. Y-piece gas temperature/humidity and the incidence of high (>40.6 mg/L) and low (<32.9 mg/L) humidity relative to the target level (36.6 mg/L) were assessed. Y-piece gas humidity was 32.0 (26.8–37.3), 22.7 (16.9–28.6), and 36.9 (35.5–38.3) mg/L {mean (95% confidence interval)} for 37-default setting, 33.5-theoretical setting, and 33.5-adjusted setting, respectively. High humidity was observed in 1 patient with 37-default setting, whereas low humidity was seen in 5 patients with 37-default setting and 8 patients with 33.5-theoretical setting. With 33.5-adjusted setting, inadequate Y-piece humidity was not observed. Potential risks of the default humidifier setting for insufficient respiratory gas humidification were highlighted in patients cooled at a paediatric/adult intensive care unit. Y-piece gas conditions can be controlled to the theoretically optimal level by adjusting the setting guided by Y-piece gas temperature/humidity.
format Article
id doaj-art-373fd40af2e14e9c8c76369b6e2db682
institution Kabale University
issn 1198-2241
1916-7245
language English
publishDate 2017-01-01
publisher Wiley
record_format Article
series Canadian Respiratory Journal
spelling doaj-art-373fd40af2e14e9c8c76369b6e2db6822025-02-03T01:06:13ZengWileyCanadian Respiratory Journal1198-22411916-72452017-01-01201710.1155/2017/83498748349874Insufficient Humidification of Respiratory Gases in Patients Who Are Undergoing Therapeutic Hypothermia at a Paediatric and Adult Intensive Care UnitYukari Tanaka0Sachiko Iwata1Masahiro Kinoshita2Kennosuke Tsuda3Shoichiro Tanaka4Naoko Hara5Ryota Shindou6Eimei Harada7Ryouji Kijima8Osamu Yamaga9Hitoe Ohkuma10Kazuo Ushijima11Teruo Sakamoto12Yushiro Yamashita13Osuke Iwata14Department of Paediatrics and Child Health, Kurume University School of Medicine, Fukuoka, JapanDepartment of Paediatrics and Child Health, Kurume University School of Medicine, Fukuoka, JapanDepartment of Paediatrics and Child Health, Kurume University School of Medicine, Fukuoka, JapanDepartment of Paediatrics and Child Health, Kurume University School of Medicine, Fukuoka, JapanDepartment of Paediatrics and Child Health, Kurume University School of Medicine, Fukuoka, JapanDepartment of Paediatrics and Child Health, Kurume University School of Medicine, Fukuoka, JapanDepartment of Paediatrics and Child Health, Kurume University School of Medicine, Fukuoka, JapanDepartment of Paediatrics and Child Health, Kurume University School of Medicine, Fukuoka, JapanDepartment of Clinical Engineering, Kurume University Hospital, Fukuoka, JapanDepartment of Clinical Engineering, Kurume University Hospital, Fukuoka, JapanDepartment of Clinical Engineering, Kurume University Hospital, Fukuoka, JapanDepartment of Anaesthesiology, Kurume University School of Medicine, Fukuoka, JapanAdvanced Emergency Medical Service Centre, Kurume University Hospital, Fukuoka, JapanDepartment of Paediatrics and Child Health, Kurume University School of Medicine, Fukuoka, JapanDepartment of Paediatrics and Child Health, Kurume University School of Medicine, Fukuoka, JapanFor cooled newborn infants, humidifier settings for normothermic condition provide excessive gas humidity because absolute humidity at saturation is temperature-dependent. To assess humidification of respiratory gases in patients who underwent moderate therapeutic hypothermia at a paediatric/adult intensive care unit, 6 patients were studied over 9 times. Three humidifier settings, 37-default (chamber-outlet, 37°C; Y-piece, 40°C), 33.5-theoretical (chamber-outlet, 33.5°C; Y-piece, 36.5°C), and 33.5-adjusted (optimised setting to achieve saturated vapour at 33.5°C using feedback from a thermohygrometer), were tested. Y-piece gas temperature/humidity and the incidence of high (>40.6 mg/L) and low (<32.9 mg/L) humidity relative to the target level (36.6 mg/L) were assessed. Y-piece gas humidity was 32.0 (26.8–37.3), 22.7 (16.9–28.6), and 36.9 (35.5–38.3) mg/L {mean (95% confidence interval)} for 37-default setting, 33.5-theoretical setting, and 33.5-adjusted setting, respectively. High humidity was observed in 1 patient with 37-default setting, whereas low humidity was seen in 5 patients with 37-default setting and 8 patients with 33.5-theoretical setting. With 33.5-adjusted setting, inadequate Y-piece humidity was not observed. Potential risks of the default humidifier setting for insufficient respiratory gas humidification were highlighted in patients cooled at a paediatric/adult intensive care unit. Y-piece gas conditions can be controlled to the theoretically optimal level by adjusting the setting guided by Y-piece gas temperature/humidity.http://dx.doi.org/10.1155/2017/8349874
spellingShingle Yukari Tanaka
Sachiko Iwata
Masahiro Kinoshita
Kennosuke Tsuda
Shoichiro Tanaka
Naoko Hara
Ryota Shindou
Eimei Harada
Ryouji Kijima
Osamu Yamaga
Hitoe Ohkuma
Kazuo Ushijima
Teruo Sakamoto
Yushiro Yamashita
Osuke Iwata
Insufficient Humidification of Respiratory Gases in Patients Who Are Undergoing Therapeutic Hypothermia at a Paediatric and Adult Intensive Care Unit
Canadian Respiratory Journal
title Insufficient Humidification of Respiratory Gases in Patients Who Are Undergoing Therapeutic Hypothermia at a Paediatric and Adult Intensive Care Unit
title_full Insufficient Humidification of Respiratory Gases in Patients Who Are Undergoing Therapeutic Hypothermia at a Paediatric and Adult Intensive Care Unit
title_fullStr Insufficient Humidification of Respiratory Gases in Patients Who Are Undergoing Therapeutic Hypothermia at a Paediatric and Adult Intensive Care Unit
title_full_unstemmed Insufficient Humidification of Respiratory Gases in Patients Who Are Undergoing Therapeutic Hypothermia at a Paediatric and Adult Intensive Care Unit
title_short Insufficient Humidification of Respiratory Gases in Patients Who Are Undergoing Therapeutic Hypothermia at a Paediatric and Adult Intensive Care Unit
title_sort insufficient humidification of respiratory gases in patients who are undergoing therapeutic hypothermia at a paediatric and adult intensive care unit
url http://dx.doi.org/10.1155/2017/8349874
work_keys_str_mv AT yukaritanaka insufficienthumidificationofrespiratorygasesinpatientswhoareundergoingtherapeutichypothermiaatapaediatricandadultintensivecareunit
AT sachikoiwata insufficienthumidificationofrespiratorygasesinpatientswhoareundergoingtherapeutichypothermiaatapaediatricandadultintensivecareunit
AT masahirokinoshita insufficienthumidificationofrespiratorygasesinpatientswhoareundergoingtherapeutichypothermiaatapaediatricandadultintensivecareunit
AT kennosuketsuda insufficienthumidificationofrespiratorygasesinpatientswhoareundergoingtherapeutichypothermiaatapaediatricandadultintensivecareunit
AT shoichirotanaka insufficienthumidificationofrespiratorygasesinpatientswhoareundergoingtherapeutichypothermiaatapaediatricandadultintensivecareunit
AT naokohara insufficienthumidificationofrespiratorygasesinpatientswhoareundergoingtherapeutichypothermiaatapaediatricandadultintensivecareunit
AT ryotashindou insufficienthumidificationofrespiratorygasesinpatientswhoareundergoingtherapeutichypothermiaatapaediatricandadultintensivecareunit
AT eimeiharada insufficienthumidificationofrespiratorygasesinpatientswhoareundergoingtherapeutichypothermiaatapaediatricandadultintensivecareunit
AT ryoujikijima insufficienthumidificationofrespiratorygasesinpatientswhoareundergoingtherapeutichypothermiaatapaediatricandadultintensivecareunit
AT osamuyamaga insufficienthumidificationofrespiratorygasesinpatientswhoareundergoingtherapeutichypothermiaatapaediatricandadultintensivecareunit
AT hitoeohkuma insufficienthumidificationofrespiratorygasesinpatientswhoareundergoingtherapeutichypothermiaatapaediatricandadultintensivecareunit
AT kazuoushijima insufficienthumidificationofrespiratorygasesinpatientswhoareundergoingtherapeutichypothermiaatapaediatricandadultintensivecareunit
AT teruosakamoto insufficienthumidificationofrespiratorygasesinpatientswhoareundergoingtherapeutichypothermiaatapaediatricandadultintensivecareunit
AT yushiroyamashita insufficienthumidificationofrespiratorygasesinpatientswhoareundergoingtherapeutichypothermiaatapaediatricandadultintensivecareunit
AT osukeiwata insufficienthumidificationofrespiratorygasesinpatientswhoareundergoingtherapeutichypothermiaatapaediatricandadultintensivecareunit