Surfactant protein D alleviates chondrocytes senescence by upregulating SIRT3/SOD2 pathway in osteoarthritis

Abstract Background Osteoarthritis (OA) is an age-related degenerative disease that affects bones and joints. The hallmark pathogenesis of OA is associated with chondrocyte senescence. Surfactant protein D (SP-D) is a member of the innate immune proteins family, which can inhibit the immune inflamma...

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Bibliographic Details
Main Authors: Huanyu Jiang, Yantao Zhang, Piyao Ji, Jianghua Ming, Yaming Li, Yan Zhou
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Molecular Medicine
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Online Access:https://doi.org/10.1186/s10020-025-01221-6
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