Ulinastatin in the treatment of radiotherapy-induced oral mucositis in locoregionally advanced nasopharyngeal carcinoma: a phase 3 randomized clinical trial

Abstract Radiotherapy-induced oral mucositis (RTOM) is a common side effect of radiotherapy in locoregionally advanced nasopharyngeal carcinoma (LA-NPC) receiving concurrent chemoradiotherapy (CCRT). In this phase 3 trial, we aim to evaluate the efficacy and safety of Ulinastatin (UTI) for the preve...

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Main Authors: Xuguang Wang, Haijun Wu, Feng Lei, Zhigang Liu, Guanzhu Shen, Xuefeng Hu, Yijing Ye, Manyi Zhu, Huageng Huang, Boyu Chen, Runda Huang, Chong Zhao, Jingjing Miao, Lin Wang
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-57884-6
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