Enhanced brain delivery and antiproliferative activity of resveratrol using milk-derived exosomes

Enhanced brain delivery and antiproliferative activity of resveratrol using milk-derived exosomes

The polyphenol resveratrol (RSV) undergoes extensive phase II metabolism, which limits its bioavailability and bioactivity, including anticancer effects. Growing preclinical evidence reinforces milk-derived exosomes (EXOs) as promising nanocarrier drugs and bioactives delivery systems. Herein, to ov...

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Main Authors: María Ángeles Ávila-Gálvez, Beatriz Garay-Mayol, Juan Antonio Giménez-Bastida, María del Carmen López de las Hazas, Carmen Mazarío-Gárgoles, Maria Alexandra Brito, Alberto Dávalos, Juan Carlos Espín, Antonio González-Sarrías
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Journal of Agriculture and Food Research
Subjects:
Exosome
Nanocarrier
Polyphenol
Resveratrol
Brain cancer
Blood-brain barrier
Online Access:http://www.sciencedirect.com/science/article/pii/S2666154324004071
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