Examining Symptom Management and Quality of Life of Loop Diuretic-Induced Overactive Bladder Among Heart Failure Patients: Physician and Patient Perspectives

Loop diuretics are strongly recommended in patients with chronic congestive heart failure (HF) to alleviate signs and symptoms of fluid overload. Loop diuretics help relieve congestive symptoms and reduce mortality, but may have side effects. This survey study examined the impact of loop diuretic-in...

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Main Authors: Xin Pan PharmD, MPH, Christopher S Wilcox MD, PhD, Bertram Pitt MD, Salim Shah MPhil, PhD, Anandi V Law B.Pharm., MS, PhD, FAPhA
Format: Article
Language:English
Published: SAGE Publishing 2025-02-01
Series:Journal of Patient Experience
Online Access:https://doi.org/10.1177/23743735251316416
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author Xin Pan PharmD, MPH
Christopher S Wilcox MD, PhD
Bertram Pitt MD
Salim Shah MPhil, PhD
Anandi V Law B.Pharm., MS, PhD, FAPhA
author_facet Xin Pan PharmD, MPH
Christopher S Wilcox MD, PhD
Bertram Pitt MD
Salim Shah MPhil, PhD
Anandi V Law B.Pharm., MS, PhD, FAPhA
author_sort Xin Pan PharmD, MPH
collection DOAJ
description Loop diuretics are strongly recommended in patients with chronic congestive heart failure (HF) to alleviate signs and symptoms of fluid overload. Loop diuretics help relieve congestive symptoms and reduce mortality, but may have side effects. This survey study examined the impact of loop diuretic-induced overactive bladder (LD-OAB) symptoms on quality of life (QOL) in HF patients; and management of OAB by HF patients and physicians. We found that (1) HF patients noted less severity of symptoms but similar QOL with non-HF. (2) HF patients (58.8%) self-managed and underreported symptoms to physicians compared to non-HF (74.8%); accordingly 65% of physicians noticed and managed symptoms. (3) Patients used mechanical solutions (pads/diapers, Kegel exercises, and fluid reduction), and physicians adjusted diuretic doses or prescribed medications for OAB. Our study highlighted that HF patients' QOL associated with bladder symptoms was not better than the non-HF group despite milder symptoms. Many HF patients either did not report or coped with/self-managed their loop diuretic-induced bladder symptoms, pointing to a need for better awareness of patient experiences and patient-physician communication.
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spelling doaj-art-36628eda9900424e9d0d439cb44ad7592025-02-06T10:03:20ZengSAGE PublishingJournal of Patient Experience2374-37432025-02-011210.1177/23743735251316416Examining Symptom Management and Quality of Life of Loop Diuretic-Induced Overactive Bladder Among Heart Failure Patients: Physician and Patient PerspectivesXin Pan PharmD, MPH0Christopher S Wilcox MD, PhD1Bertram Pitt MD2Salim Shah MPhil, PhD3Anandi V Law B.Pharm., MS, PhD, FAPhA4 Department of Pharmacy Practice and Administration, College of Pharmacy, Western University of Health Sciences, Pomona, CA, USA Division of Nephrology and Hypertension and Hypertension Center, Georgetown University, Washington, DC, USA Department of Internal Medicine, Division of Cardiology, University of Michigan School of Medicine, Ann Arbor, MI, USA Sarfez Pharmaceuticals Inc., Vienna, VA, USA Department of Pharmacy Practice and Administration, College of Pharmacy, Western University of Health Sciences, Pomona, CA, USALoop diuretics are strongly recommended in patients with chronic congestive heart failure (HF) to alleviate signs and symptoms of fluid overload. Loop diuretics help relieve congestive symptoms and reduce mortality, but may have side effects. This survey study examined the impact of loop diuretic-induced overactive bladder (LD-OAB) symptoms on quality of life (QOL) in HF patients; and management of OAB by HF patients and physicians. We found that (1) HF patients noted less severity of symptoms but similar QOL with non-HF. (2) HF patients (58.8%) self-managed and underreported symptoms to physicians compared to non-HF (74.8%); accordingly 65% of physicians noticed and managed symptoms. (3) Patients used mechanical solutions (pads/diapers, Kegel exercises, and fluid reduction), and physicians adjusted diuretic doses or prescribed medications for OAB. Our study highlighted that HF patients' QOL associated with bladder symptoms was not better than the non-HF group despite milder symptoms. Many HF patients either did not report or coped with/self-managed their loop diuretic-induced bladder symptoms, pointing to a need for better awareness of patient experiences and patient-physician communication.https://doi.org/10.1177/23743735251316416
spellingShingle Xin Pan PharmD, MPH
Christopher S Wilcox MD, PhD
Bertram Pitt MD
Salim Shah MPhil, PhD
Anandi V Law B.Pharm., MS, PhD, FAPhA
Examining Symptom Management and Quality of Life of Loop Diuretic-Induced Overactive Bladder Among Heart Failure Patients: Physician and Patient Perspectives
Journal of Patient Experience
title Examining Symptom Management and Quality of Life of Loop Diuretic-Induced Overactive Bladder Among Heart Failure Patients: Physician and Patient Perspectives
title_full Examining Symptom Management and Quality of Life of Loop Diuretic-Induced Overactive Bladder Among Heart Failure Patients: Physician and Patient Perspectives
title_fullStr Examining Symptom Management and Quality of Life of Loop Diuretic-Induced Overactive Bladder Among Heart Failure Patients: Physician and Patient Perspectives
title_full_unstemmed Examining Symptom Management and Quality of Life of Loop Diuretic-Induced Overactive Bladder Among Heart Failure Patients: Physician and Patient Perspectives
title_short Examining Symptom Management and Quality of Life of Loop Diuretic-Induced Overactive Bladder Among Heart Failure Patients: Physician and Patient Perspectives
title_sort examining symptom management and quality of life of loop diuretic induced overactive bladder among heart failure patients physician and patient perspectives
url https://doi.org/10.1177/23743735251316416
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