Recombinant SpTransformer proteins bind to specific sites on sea urchin phagocytes and modulate SpTransformer gene expression and immune responsiveness

Recombinant SpTransformer proteins bind to specific sites on sea urchin phagocytes and modulate SpTransformer gene expression and immune responsiveness

IntroductionThe California purple sea urchin, Strongylocentrotus purpuratus, relies exclusively on an innate immune system to survive in its pathogen rich marine environment. Central to this defense is the SpTransformer (SpTrf) gene family that is unique to the euechinoid group of echinoderms. These...

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Bibliographic Details
Main Authors: Ryley S. Crow, Leon Grayfer, L. Courtney Smith
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Immunology
Subjects:
echinoderm
Strongylocentrotus purpuratus
coelomocytes
innate immunity
immune effector proteins
auto-regulation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1496832/full
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