Galectin-3 plays a key role in controlling infection by Toxoplasma gondii in human trophoblast cells and human villous explants

Galectin-3 plays a key role in controlling infection by Toxoplasma gondii in human trophoblast cells and human villous explants

Galectin-3 (Gal-3) is a β-galactoside-binding lectin expressed in cells of the placental microenvironment. This lectin is involved in various biological processes, such as modulation of the immune system and control of parasitic illness. Toxoplasma gondii infection can lead to congenital transmissio...

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Main Authors: Luana Carvalho Luz, Mayara Ribeiro, Samuel Cota Teixeira, Guilherme de Souza, Marina Paschoalino, Daniel Pereira Sousa, Alessandra Monteiro Rosini, Natalia Carine Lima dos Santos, Rafael Martins de Oliveira, Joed Pires de Lima Júnior, Izadora Santos Damasceno, Marcos Paulo Oliveira Almeida, Matheus Carvalho Barbosa, Celene Maria de Oliveira Simões Alves, Claudio Vieira da Silva, Bellisa Freitas Barbosa, Eloisa Amália Vieira Ferro
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
maternal-fetal interface
congenital toxoplasmosis
placental
Gal-3
immune response
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2024.1459810/full
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https://www.frontiersin.org/articles/10.3389/fcimb.2024.1459810/full

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