Genome wide association study of fetal hemoglobin in sickle cell anemia in Tanzania.

<h4>Background</h4>Fetal hemoglobin (HbF) is an important modulator of sickle cell disease (SCD). HbF has previously been shown to be affected by variants at three loci on chromosomes 2, 6 and 11, but it is likely that additional loci remain to be discovered.<h4>Methods and finding...

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Main Authors: Siana Nkya Mtatiro, Tarjinder Singh, Helen Rooks, Josephine Mgaya, Harvest Mariki, Deogratius Soka, Bruno Mmbando, Evarist Msaki, Iris Kolder, Swee Lay Thein, Stephan Menzel, Sharon E Cox, Julie Makani, Jeffrey C Barrett
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0111464
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