Real world study in Italian public hospital with Efgartigimod in patients affected by generalized myasthenia gravis: influence of clinical and serological factors

Real world study in Italian public hospital with Efgartigimod in patients affected by generalized myasthenia gravis: influence of clinical and serological factors

BackgroundMyasthenia gravis (MG) is an autoimmune neuromuscular disorder caused by IgG autoantibodies targeting the neuromuscular junction. Recycling of IgG is mediated by the neonatal Fc receptor (FcRn). Efgartigimod, an Fc fragment of human IgG1, has demonstrated efficacy in MG; however, the clini...

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Bibliographic Details
Main Authors: Manlio Sgarzi, Paolo Paone, Giorgia Camera, Emanuela Agazzi, Sara Mazzoleni, Francesca Martorana, Dario Alimonti
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Neurology
Subjects:
Myasthenia Gravis
Efgartigimod
Thymectomy
T cells
AChR
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2025.1555068/full
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