Evaluation of the Biomarkers HMGB1 and IL-6 as Predictors of Mortality in Cirrhotic Patients with Acute Kidney Injury

Background. Acute kidney injury (AKI) affects from 20% to 50% of cirrhotic patients, and the one-month mortality rate is 60%. The main cause of AKI is bacterial infection, which worsens circulatory dysfunction through the release of HMGB1 and IL-6. Objectives. To evaluate HMGB1 and IL-6 as biomarker...

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Main Authors: Célio Geraldo de Oliveira Gomes, Marcus Vinicius Melo de Andrade, Ludmila Resende Guedes, Henrique Carvalho Rocha, Roberto Gardone Guimarães, Fernando Antônio Castro Carvalho, Eduardo Garcia Vilela
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2020/2867241
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