Biophysical and spectroscopical insights into structural modulation of species in the aggregation pathway of superoxide dismutase 1
Abstract Superoxide dismutase 1 (SOD1) aggregation is implicated in the development of Amyotrophic Lateral Sclerosis (ALS). Despite knowledge of the role of SOD1 aggregation, the mechanistic understanding remains elusive. Our investigation aimed to unravel the complex steps involved in SOD1 aggregat...
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Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2025-01-01
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Series: | Communications Chemistry |
Online Access: | https://doi.org/10.1038/s42004-025-01421-5 |
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