Engineered a dual-targeting biomimetic nanomedicine for pancreatic cancer chemoimmunotherapy

Abstract The therapeutic effect of chemotherapeutics such as gemcitabine against pancreatic cancer is considerably attenuated by immune-suppressive tumor microenvironment. Improvement of chemotherapeutic efficacy by targeting tumor-associated macrophage and reprograming tumor microenvironment to enh...

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Bibliographic Details
Main Authors: Meng Wang, Qida Hu, Junmin Huang, Xinyu Zhao, Shiyi Shao, Fu Zhang, Zhuo Yao, Yuan Ping, Tingbo Liang
Format: Article
Language:English
Published: BMC 2022-02-01
Series:Journal of Nanobiotechnology
Online Access:https://doi.org/10.1186/s12951-022-01282-3
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