Evaluating the antimicrobial and anti-inflammatory mechanisms of dexmedetomidine in managing bone infection: a laboratory perspective

Evaluating the antimicrobial and anti-inflammatory mechanisms of dexmedetomidine in managing bone infection: a laboratory perspective

Abstract Background Osteomyelitis involves bone destruction, impaired bone formation, and systemic inflammation. Dexmedetomidine (DXMT) possesses antioxidant, anti-inflammatory, and anti-apoptotic properties alongside sedative and analgesic effects. This study evaluates DXMT's effects on marker...

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Main Authors: Merve Hayriye Kocaoğlu, Günseli Çubukçuoğlu Deniz, Duru Aras-Tosun, Evrim Güneş Altuntaş, Erkan Tuncay
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Musculoskeletal Disorders
Subjects:
Anti-inflammation
Antimicrobial
Dexmedetomidine
Osteoblast
Osteomyelitis
Reactive Oxygen Species (ROS)
Online Access:https://doi.org/10.1186/s12891-025-08555-6
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https://doi.org/10.1186/s12891-025-08555-6

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