Effect of a high-fat diet and iron overload on erythropoiesis in mice

Background: Insulin and iron availability stimulate and regulate erythropoiesis, respectively. The effects of hyperinsulinemia and/or iron overload on erythroid differentiation are unclear. Methodology: Male C57Bl/6J wild-type (WT) mice were fed a high-fat diet (HFD) (to produce hyperinsulinemia) or...

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Bibliographic Details
Main Authors: Joe Varghese, Jithu James Varghese, Molly Jacob
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Biochemistry and Biophysics Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2405580825000068
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