Osteocytic vinculin controls bone mass by modulating Mef2c-driven sclerostin expression in mice
Abstract The focal adhesion (FA) is the structural basis of the cell-extracellular matrix crosstalk and plays important roles in control of organ formation and function. Here we show that expression of FA protein vinculin is dramatically reduced in osteocytes in patients with aging-related osteoporo...
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| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2025-08-01
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| Series: | Bone Research |
| Online Access: | https://doi.org/10.1038/s41413-025-00452-x |
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