Innovative bioinks for 3D bioprinting: Exploring technological potential and regulatory challenges
The field of three dimensional (3D) bioprinting has witnessed significant advancements, with bioinks playing a crucial role in enabling the fabrication of complex tissue constructs. This review explores the innovative bioinks that are currently shaping the future of 3D bioprinting, focusing on their...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2025-01-01
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| Series: | Journal of Tissue Engineering |
| Online Access: | https://doi.org/10.1177/20417314241308022 |
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| author | Vidhi Mathur Prachi Agarwal Meghana Kasturi Varadharajan Srinivasan Raviraja N Seetharam Kirthanashri S Vasanthan |
| author_facet | Vidhi Mathur Prachi Agarwal Meghana Kasturi Varadharajan Srinivasan Raviraja N Seetharam Kirthanashri S Vasanthan |
| author_sort | Vidhi Mathur |
| collection | DOAJ |
| description | The field of three dimensional (3D) bioprinting has witnessed significant advancements, with bioinks playing a crucial role in enabling the fabrication of complex tissue constructs. This review explores the innovative bioinks that are currently shaping the future of 3D bioprinting, focusing on their composition, functionality, and potential for tissue engineering, drug delivery, and regenerative medicine. The development of bioinks, incorporating natural and synthetic materials, offers unprecedented opportunities for personalized medicine. However, the rapid technological progress raises regulatory challenges regarding safety, standardization, and long-term biocompatibility. This paper addresses these challenges, examining the current regulatory frameworks and the need for updated guidelines to ensure patient safety and product efficacy. By highlighting both the technological potential and regulatory hurdles, this review offers a comprehensive overview of the future landscape of bioinks in bioprinting, emphasizing the necessity for cross-disciplinary collaboration between scientists, clinicians, and regulatory bodies to achieve successful clinical applications. |
| format | Article |
| id | doaj-art-34572a07f96148b092d3c40a03a57772 |
| institution | Kabale University |
| issn | 2041-7314 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of Tissue Engineering |
| spelling | doaj-art-34572a07f96148b092d3c40a03a577722025-01-21T08:03:20ZengSAGE PublishingJournal of Tissue Engineering2041-73142025-01-011610.1177/20417314241308022Innovative bioinks for 3D bioprinting: Exploring technological potential and regulatory challengesVidhi Mathur0Prachi Agarwal1Meghana Kasturi2Varadharajan Srinivasan3Raviraja N Seetharam4Kirthanashri S Vasanthan5Manipal Centre for Biotherapeutics Research, Manipal Academy of Higher Education, Manipal, Karnataka, IndiaManipal Centre for Biotherapeutics Research, Manipal Academy of Higher Education, Manipal, Karnataka, IndiaDepartment of Mechanical Engineering, University of Michigan, Dearborn, MI, USADepartment of Civil Engineering, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal, Karnataka, IndiaManipal Centre for Biotherapeutics Research, Manipal Academy of Higher Education, Manipal, Karnataka, IndiaManipal Centre for Biotherapeutics Research, Manipal Academy of Higher Education, Manipal, Karnataka, IndiaThe field of three dimensional (3D) bioprinting has witnessed significant advancements, with bioinks playing a crucial role in enabling the fabrication of complex tissue constructs. This review explores the innovative bioinks that are currently shaping the future of 3D bioprinting, focusing on their composition, functionality, and potential for tissue engineering, drug delivery, and regenerative medicine. The development of bioinks, incorporating natural and synthetic materials, offers unprecedented opportunities for personalized medicine. However, the rapid technological progress raises regulatory challenges regarding safety, standardization, and long-term biocompatibility. This paper addresses these challenges, examining the current regulatory frameworks and the need for updated guidelines to ensure patient safety and product efficacy. By highlighting both the technological potential and regulatory hurdles, this review offers a comprehensive overview of the future landscape of bioinks in bioprinting, emphasizing the necessity for cross-disciplinary collaboration between scientists, clinicians, and regulatory bodies to achieve successful clinical applications.https://doi.org/10.1177/20417314241308022 |
| spellingShingle | Vidhi Mathur Prachi Agarwal Meghana Kasturi Varadharajan Srinivasan Raviraja N Seetharam Kirthanashri S Vasanthan Innovative bioinks for 3D bioprinting: Exploring technological potential and regulatory challenges Journal of Tissue Engineering |
| title | Innovative bioinks for 3D bioprinting: Exploring technological potential and regulatory challenges |
| title_full | Innovative bioinks for 3D bioprinting: Exploring technological potential and regulatory challenges |
| title_fullStr | Innovative bioinks for 3D bioprinting: Exploring technological potential and regulatory challenges |
| title_full_unstemmed | Innovative bioinks for 3D bioprinting: Exploring technological potential and regulatory challenges |
| title_short | Innovative bioinks for 3D bioprinting: Exploring technological potential and regulatory challenges |
| title_sort | innovative bioinks for 3d bioprinting exploring technological potential and regulatory challenges |
| url | https://doi.org/10.1177/20417314241308022 |
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