Nuclear keratin 6A upregulates human papillomavirus oncogene expression through TEAD1 interaction

Nuclear keratin 6A upregulates human papillomavirus oncogene expression through TEAD1 interaction

Abstract Background Human papillomavirus (HPV) oncogenes, E6 and E7, play a critical role in cervical carcinogenesis, and their expression is regulated by cellular transcription factors bound to the long control region (LCR) in the HPV genome. To elucidate the mechanisms of HPV-induced carcinogenesi...

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Bibliographic Details
Main Authors: Tomoya Miyamura, Seiichiro Mori, Mamiko Onuki, Akihiko Sekizawa, Koji Matsumoto, Iwao Kukimoto
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Virology Journal
Subjects:
Human papillomavirus
Viral oncogene
Gene expression
Keratin 6A
Cervical cancer
Online Access:https://doi.org/10.1186/s12985-025-02832-5
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https://doi.org/10.1186/s12985-025-02832-5

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