Molecular Mechanisms of Neurodegeneration Related to C9orf72 Hexanucleotide Repeat Expansion
Two clinically distinct diseases, amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), have recently been classified as two extremes of the FTD/ALS spectrum. The neuropathological correlate of FTD is frontotemporal lobar degeneration (FTLD), characterized by tau-, TDP-43-, and FUS-...
Saved in:
Main Authors: | Mirjana Babić Leko, Vera Župunski, Jason Kirincich, Dinko Smilović, Tibor Hortobágyi, Patrick R. Hof, Goran Šimić |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2019-01-01
|
Series: | Behavioural Neurology |
Online Access: | http://dx.doi.org/10.1155/2019/2909168 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Oligonucleotide-Based Therapy for FTD/ALS Caused by the C9orf72 Repeat Expansion: A Perspective
by: Stephanie A. Fernandes, et al.
Published: (2013-01-01) -
C9orf72 Alleviates DSS‑Induced Ulcerative Colitis via the cGAS‐STING Pathway
by: Yue Wang, et al.
Published: (2025-01-01) -
Kaempferol enhances ER-mitochondria coupling and protects motor neurons from mitochondrial dysfunction and ER stress in C9ORF72-ALS
by: Federica Pilotto, et al.
Published: (2025-02-01) -
Repeated Intra-Arterial Thrombectomy within 72 Hours in a Patient with a Clear Contraindication for Intravenous Thrombolysis
by: Mona Laible, et al.
Published: (2015-01-01) -
Temporal and spatial characterization of keratinocytes supporting orf virus replication
by: Byung-Joon Seung, et al.
Published: (2025-01-01)