Development and validation of a hypoxia-immune-based microenvironment gene signature for predicting survival in non-small cell lung cancer

Development and validation of a hypoxia-immune-based microenvironment gene signature for predicting survival in non-small cell lung cancer

Abstract Background This study aims to establish a hypoxia-immune-related gene signature within the tumor microenvironment (TME) to reliably predict prognosis in non-small cell lung cancer (NSCLC). Methods Transcriptomic profiles and clinical data of lung adenocarcinoma (LUAD) and lung squamous cell...

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Bibliographic Details
Main Authors: Xiangwu Zhang, Rongxian Zhou, Guangqiang Zhao, Wanling Chen, Ping Zhao, Yunchao Huang, Qiubo Huang, Lianhua Ye
Format: Article
Language:English
Published: Springer 2025-08-01
Series:Discover Oncology
Subjects:
Non-small cell lung cancer
Hypoxia
Immunity
Genetic markers
Prognostic model
Online Access:https://doi.org/10.1007/s12672-025-03319-z
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https://doi.org/10.1007/s12672-025-03319-z

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