Randomized Trial of Lower-Dose Roxadustat Efficacy and Safety in Non–Dialysis-Dependent CKD-Associated Anemia

Randomized Trial of Lower-Dose Roxadustat Efficacy and Safety in Non–Dialysis-Dependent CKD-Associated Anemia

Introduction: Different starting doses of roxadustat are used for treating anemia in chronic kidney disease (CKD). We tested the noninferiority of weight-based lower starting dose compared with standard starting dose roxadustat for anemia in stage 3 to 5 CKD without dialysis. Methods: Patients were...

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Main Authors: Ping Li, Xuefeng Sun, Li Zhang, Hongli Lin, Niansong Wang, Yuehong Li, Sumei Zhao, Ping Fu, Hong Cheng, Zhiyong Guo, Wanhong Lu, Yani He, Fengmin Shao, Qiang He, Yiqing Wu, Cuihua Huang, Shuting Pan, Guangyan Cai, Xiangmei Chen, Shiren Sun, Wei Liang, Hongtao Yang, Zhaohui Ni, Qiongqiong Yang, Wenge Li, Aihua Zhang, Guojuan Zhang, Gengru Jiang, Bo Lin, Yanning Zhang, Wenhu Liu, Yonghui Mao, Jinsheng Xu, Weiping Liu, Song Wang, Xiaodong Zhang, Jurong Yang, Hongwei Jiang
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Kidney International Reports
Subjects:
anemia
chronic kidney disease
efficacy
hemoglobin variability
roxadustat
Online Access:http://www.sciencedirect.com/science/article/pii/S246802492500052X
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