scaDA: A novel statistical method for differential analysis of single-cell chromatin accessibility sequencing data.

Single-cell ATAC-seq sequencing data (scATAC-seq) has been widely used to investigate chromatin accessibility on the single-cell level. One important application of scATAC-seq data analysis is differential chromatin accessibility (DA) analysis. However, the data characteristics of scATAC-seq such as...

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Bibliographic Details
Main Authors: Fengdi Zhao, Xin Ma, Bing Yao, Qing Lu, Li Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-08-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1011854
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