MiR‐182‐3p targets TRF2 and impairs tumor growth of triple‐negative breast cancer

MiR‐182‐3p targets TRF2 and impairs tumor growth of triple‐negative breast cancer

Abstract The telomeric repeat‐binding factor 2 (TRF2) is a telomere‐capping protein that plays a key role in the maintenance of telomere structure and function. It is highly expressed in different cancer types, and it contributes to cancer progression. To date, anti‐cancer strategies to target TRF2...

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Main Authors: Roberto Dinami, Luca Pompili, Eleonora Petti, Manuela Porru, Carmen D'Angelo, Serena Di Vito, Angela Rizzo, Virginia Campani, Giuseppe De Rosa, Alejandra Bruna, Violeta Serra, Miguel Mano, Mauro Giacca, Carlo Leonetti, Gennaro Ciliberto, Madalena Tarsounas, Antonella Stoppacciaro, Stefan Schoeftner, Annamaria Biroccio
Format: Article
Language:English
Published: Springer Nature 2022-11-01
Series:EMBO Molecular Medicine
Subjects:
miR‐182‐3p
target therapy
telomeres
TRF2
triple‐negative breast cancer
Online Access:https://doi.org/10.15252/emmm.202216033
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https://doi.org/10.15252/emmm.202216033

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