Aryana-bs: context-aware alignment of bisulfite-sequencing reads

Aryana-bs: context-aware alignment of bisulfite-sequencing reads

Abstract Background DNA methylation is essential in various biological processes, including imprinting, development, inflammation, and numerous disorders, such as cancer. Bisulfite sequencing (BS) serves as the gold standard for measuring DNA methylation at single-base resolution by converting unmet...

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Bibliographic Details
Main Authors: Hassan Nikaein, Ali Sharifi-Zarchi, Afsoon Afzal, Saeedeh Ezzati, Farzane Rasti, Hamidreza Chitsaz, Govindarajan Kunde-Ramamoorthy
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Bioinformatics
Subjects:
DNA methylation
bisulfite sequencing
alignment
CpG island
Online Access:https://doi.org/10.1186/s12859-025-06182-5
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