The MICOS Complex Subunit Mic60 is Hijacked by Intracellular Bacteria to Manipulate Mitochondrial Dynamics and Promote Bacterial Pathogenicity

The MICOS Complex Subunit Mic60 is Hijacked by Intracellular Bacteria to Manipulate Mitochondrial Dynamics and Promote Bacterial Pathogenicity

Abstract Host mitochondria undergo fission and fusion, which bacteria often exploit for their infections. In this study, the underlying molecular mechanisms are aimed to clarify through which Listeria monocytogenes (L. monocytogenes), a human bacterial pathogen, manipulates mitochondrial dynamics to...

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Main Authors: Changyong Cheng, Mianmian Chen, Jing Sun, Jiali Xu, Simin Deng, Jing Xia, Yue Han, Xian Zhang, Jing Wang, Lei Lei, Ruidong Zhai, Qin Wu, Weihuan Fang, Houhui Song
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:Advanced Science
Subjects:
host‐microbe interplay
listeriolysin O (LLO)
Mic60
MICOS
mitochondrial fragmentation
Online Access:https://doi.org/10.1002/advs.202406760
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https://doi.org/10.1002/advs.202406760

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